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  • Try not to take Zyban right at bedtime because it may cause problems falling asleep. If you are sensitive to Zyban and feel too wound-up, talk to your health care provider. This usually passes in a few days. Also, some people can quit using one Zyban a day.
  • If you feel irritable when you stop nicotine, you can use either the nicotine patch or the gum with Zyban for extra support. Zyban is not nicotine. Using both products together is safe.
  • The company that makes Zyban recommends that you stay on the medicine for at least 7 to 12 weeks. Physical withdrawal from nicotine is over in two weeks but the extra time on the medication supports you while you learn to live as a non-smoker. You need to get into the car, visit with friends, finish a meal and talk on the phone many times before the behavioral cue to smoke fades away. Zyban makes this process easier.
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